Interesting question, given the circumstances. Mizzou was picked 10th in the preseason SEC poll and the Tigers will need to climb to sixth of seventh to make the NCAA Tournament. Their strength of schedule will be fine. Their experience will be a plus, especially in the backcourt.
During a season where players will come and go due to COVID, Mizzou could have an edge IF they can avoid major injuries (unlike the last 3 years) and IF they can eight or nine virus-free players ready at all times. They have lots of depth, size and interchangeabe parts. They could be better prepared than many teams to navigate a weird season.
But . . . to this point Cuonzo Martin hasn't had much luck getting players to improve from year to year. In fact, Mark Smth, Javon Pickett and Torrence Watson all regressed last season. This team lacks obvious take-over players -- and that is especially critical since the team has not been able to run an efficient offense that produces consistently good looks at the basket.
IF Martin can fix his Xs and Os after studying NBA offenses and IF playmaker Drew Buggs can make the offense less clunky, then the Tigers get interesting. IF the Tigers can score on off-ball cuts to the basket, get more clean dribble drives to the rim and get into a catch-and-shoot rhythm from three-point range, then this could be a surprising team.
Lots of ifs in there, but there is also more potential than folks realize. We saw glimpses of that late last season.